Florence, SC → Tampa, FL
459 mi · 9h 10m (driving)
Current Risk
High Risk
Freeze Watch in effect — consider delaying
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Florence
55°
Colleton County
62°
31.1°
62°
Putnam County
69°
Tampa
63°
Trip Briefing
4 segments · 459 mi · 9h 11m
Weather
☀️ Clear sky
62°F, wind 12 mph
Rest Stops
14
Restrooms, Truck svc, water
Cameras
4 live
Clear driving conditions expected
Rest stops in this segment:
- ● Pilot Travel Center
- ● TA
- ● Rest Area 🚻
Weather May Slow Traffic
Active weather advisory — expect slower travel
Traffic Cameras
See recent road conditions along your route
Images are snapshots updated periodically by state DOTs. Timestamps shown in images indicate when each photo was captured.
Choose your route:
Selected Route
Via I-20 Bus → I-95 South → ... → I-75 South → I-275
Cameras shown are along this computed route
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50202
Florence, SC ·
50208
Florence, SC ·
10260
Columbia, SC ·
80031
Charleston, SC ·
60227
Charleston, SC ·
GDOT-1256: I-95 S before SR21 MM 112 (Effingham)
GA · SB
GDOT-1249: I-95 S at ChurchillRd MM 55 (McIntosh)
GA · SB
GDOT-1414: I-95 S before HarrietsBluffRd MM 7.6 (Camden)
GA · SB
I-95 N of Airport Rd
FL · SB
I-75 @ MM 355.1 SB
FL · SB
I-75 @ MM 339.1 SB
FL · SB
I-75 at MM 299.2
FL · SB
Rest Stops Along Your Route
73 stops available
Swipe to see moreShowing 1-2 of 73
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⚡ Recent Weather Events on This Route
Premium users received alerts for these conditions:
- 🌧️Nov 11: Rain advisory for afternoon departures
- ❄️Nov 9: Snow expected at higher elevations - consider earlier departure
- 🌫️Nov 6: Dense fog warning for morning travel
Don't miss the next alert →
Driving from Florence, SC to Tampa, FL covers 459 miles in roughly 9h 10m of drive time, crossing state lines. We track 12 live traffic cameras, 73 rest areas and 2 active weather alerts along this corridor so you can plan around them. Most drivers do this trip in one day; weather along the route matters more than the forecast at either endpoint, since you'll cross several climate zones.
7-Day Driving Outlook
Today
Nov 13
60° / 55°
No precip
Tomorrow
Nov 14
55° / 41°
No precip
Sun
Nov 15
55° / 37°
No precip
Mon
Nov 16
56° / 39°
No precip
Tue
Nov 17
59° / 39°
No precip
Wed
Nov 18
62° / 39°
No precip
Thu
Nov 19
66° / 42°
No precip
🗓️ Weekend Outlook
Saturday
Good to Go🌤️ Mainly clear at origin, ☀️ Clear sky at destination
Sunday
Good to Go☀️ Clear sky at origin, 🌤️ Mainly clear at destination
Plan This Route
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Current Conditions
Florence, SC
55°F
Wind: 8 mph
Tampa, FL
63°F
Wind: 7 mph
Weather data updated in real-time
Driving from Florence, SC to Tampa, FL
The 459-mile drive from Florence, South Carolina to Tampa, Florida takes approximately 9h 10m under normal conditions. Weather along this route can vary significantly, especially along coastal regions where fog and marine weather can impact visibility. Route Outlook helps you find the safest time to travel by showing you weather conditions at every point along your route, timed to when you'll actually be there.
This long-distance route crosses state lines from South Carolina into Florida, connecting Florence and Tampa. Covering 459 miles, this is a substantial drive that will take you through diverse terrain and weather patterns. Planning ahead with real-time conditions along the entire route — not just at your destination — is essential for a safe trip.
Common Weather Hazards on This Route
- Severe thunderstorms and flash flooding (spring and summer)
- Hurricane and tropical storm impacts (June through November)
Seasonal Driving Considerations
Coastal weather on this route can shift quickly. Marine fog is common during morning hours, especially in spring and fall, reducing visibility to near zero. Hurricane season (June through November) can bring extended road closures and dangerous conditions. During fair weather, coastal routes offer scenic driving — but always verify conditions with live traffic cameras before heading out.
Best Time to Drive Florence to Tampa
For medium-distance drives like this 459-mile route, consider starting in the early morning to arrive before afternoon storms develop. Check the 7-day forecast above to find a day with favorable conditions along the entire route.
Driving Strategy
A 459-mile drive from Florence to Tampa takes a significant part of the day. Plan at least one fuel and rest stop along the way. If your route crosses elevation changes or state lines, expect weather conditions to shift mid-trip. Monitor the segment-by-segment forecast rather than just checking destination weather. Starting early in the morning typically avoids afternoon storm development and rush-hour congestion near urban areas.
Pro Tip
Use Route Outlook's departure optimizer to find the best time to leave. Our 4D trajectory engine considers weather at each point along your route at the exact time you'll be there — not just at your destination. It also integrates live data from traffic cameras, DOT 511 feeds, and road weather sensors.
Frequently Asked Questions
How long is the drive from Florence to Tampa?
The drive is approximately 459 miles and takes about 9h 10m under normal traffic and weather conditions. Severe weather can add significant time to your trip.
What's the best day to drive this route?
Based on current forecasts, Sunday, Nov 15 looks ideal. Clear conditions expected along the entire route
Is it safe to drive from Florence to Tampa today?
Current conditions show high risk along this route. Conditions look favorable for travel. Always stay alert and adjust speed for changing conditions.
Are there rest areas on the Florence to Tampa route?
Yes, there are 73 rest areas along this route. Facilities include restrooms, parking, and in some cases picnic areas and vending machines. Rest stops are spaced throughout the drive, so you'll never be too far from a break.
Can I see live traffic cameras on this route?
Yes, Route Outlook shows 12 live traffic cameras along this route, sourced from state DOT feeds. You can check road visibility, traffic flow, and pavement conditions in real time before and during your drive.
What highways does this route use?
This route primarily uses I-95 South, I-75 South. Conditions can vary between highway segments, so check live camera feeds and road condition reports for each stretch before departing.
Are there any road closures on this route right now?
No significant incidents or road closures are currently reported along this route. Conditions can change quickly — this page updates automatically with the latest data from state DOT 511 systems.
Related Driving Guides
Finding the Safest Time to Drive: A Data-Driven Approach
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🛣️How to Check Road Conditions Before a Trip: All Your Options
A practical guide to every method for checking driving conditions--weather apps, 511 sites, traffic cameras, radio, and more. Pros, cons, and when to use each.
🧠Route Intelligence: The Smarter Way to Plan Road Trips
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