Greenville, FL → Memphis, TN
493 mi · 9h 51m (driving)
Current Risk
High Risk
Freeze Warning in effect — consider delaying
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Greenville
50°
Henry County
52°
Chilton County
49°
Amory
48°
Memphis
37°
Trip Briefing
4 segments · 493 mi · 9h 52m
Weather
☀️ Clear sky
52°F, wind 7 mph
Rest Stops
14
Restrooms, Truck svc
Cameras
12 live
Clear driving conditions expected
Rest stops in this segment:
- ● Jefferson County Rest Area Westbound 🚻
- ● Leon County Rest Area Westbound 🚻
- ● Pilot Travel Center
Weather May Slow Traffic
Active weather advisory — expect slower travel
Traffic Cameras
See recent road conditions along your route
Images are snapshots updated periodically by state DOTs. Timestamps shown in images indicate when each photo was captured.
Choose your route:
Selected Route
Via US-221 → I-10 West → ... → Doctor Martin Luther King Junior Expressway → I-40 West
Cameras shown are along this computed route
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I10-MM 240.3 WB- E of Overstreet Ave
FL · WB
I-10 W of US-221 WB
FL · WB
I-10 @ MM 238.2
FL · WB
MM 238.1 WB-TPS-DMS
FL · WB
MM 234.5 Rest Area WB
FL · WB
I10-MM 231.5 WB
FL · WB
I10-MM 228.5 WB- Turkey Scratch Rd
FL · WB
I10-MM 226.8 WB
FL · WB
I10-MM 223.8 WB-E of Waukeenah Hwy
FL · WB
I10-MM 220.0 WB- E of Old Lloyd Rd
FL · WB
MM 194.4 Rest Area-WB
FL · WB
I10-MM 141.8M SR-71
FL · WB
Rest Stops Along Your Route
44 stops available
Swipe to see moreShowing 1-2 of 44
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⚡ Recent Weather Events on This Route
Premium users received alerts for these conditions:
- 🌧️Nov 12: Rain advisory for afternoon departures
- ❄️Nov 10: Snow expected at higher elevations - consider earlier departure
- 🌫️Nov 7: Dense fog warning for morning travel
Don't miss the next alert →
Driving from Greenville, FL to Memphis, TN covers 493 miles in roughly 9h 51m of drive time, crossing state lines. We track 12 live traffic cameras, 44 rest areas and 3 active weather alerts along this corridor so you can plan around them. Most drivers do this trip in one day; weather along the route matters more than the forecast at either endpoint, since you'll cross several climate zones.
7-Day Driving Outlook
Today
Nov 14
59° / 50°
No precip
Tomorrow
Nov 15
62° / 40°
No precip
Mon
Nov 16
62° / 44°
No precip
Tue
Nov 17
68° / 50°
No precip
Wed
Nov 18
70° / 51°
No precip
Thu
Nov 19
74° / 54°
No precip
Fri
Nov 20
75° / 56°
No precip
🗓️ Weekend Outlook
Saturday
Good to Go☀️ Clear sky at origin, ⛅ Partly cloudy at destination
Sunday
Good to Go⛅ Partly cloudy at origin, ⛅ Partly cloudy at destination
Plan This Route
Get hour-by-hour weather forecasts, real-time traffic, and find the optimal departure time.
🚗 Live traffic included
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Current Conditions
Greenville, FL
50°F
Wind: 7 mph
Memphis, TN
37°F
Wind: 5 mph
Weather data updated in real-time
Driving from Greenville, FL to Memphis, TN
The 493-mile drive from Greenville, Florida to Memphis, Tennessee takes approximately 9h 51m under normal conditions. Weather along this route can vary significantly, especially across varying terrain where weather conditions can change rapidly. Route Outlook helps you find the safest time to travel by showing you weather conditions at every point along your route, timed to when you'll actually be there.
This long-distance route crosses state lines from Florida into Tennessee, connecting Greenville and Memphis. Covering 493 miles, this is a substantial drive that will take you through diverse terrain and weather patterns. Planning ahead with real-time conditions along the entire route — not just at your destination — is essential for a safe trip.
Common Weather Hazards on This Route
- Severe thunderstorms and flash flooding (spring and summer)
- Hurricane and tropical storm impacts (June through November)
Seasonal Driving Considerations
Weather along this route varies by season. Winter months can bring snow, ice, and reduced visibility, while summer may see thunderstorms, heat-related road issues, or construction zones. Spring and fall generally offer the most comfortable driving conditions but can still surprise with sudden weather changes. Regardless of season, checking real-time conditions along your entire route before departing can help you avoid the worst of it.
Best Time to Drive Greenville to Memphis
For medium-distance drives like this 493-mile route, consider starting in the early morning to arrive before afternoon storms develop. Check the 7-day forecast above to find a day with favorable conditions along the entire route.
Driving Strategy
A 493-mile drive from Greenville to Memphis takes a significant part of the day. Plan at least one fuel and rest stop along the way. If your route crosses elevation changes or state lines, expect weather conditions to shift mid-trip. Monitor the segment-by-segment forecast rather than just checking destination weather. Starting early in the morning typically avoids afternoon storm development and rush-hour congestion near urban areas.
Pro Tip
Use Route Outlook's departure optimizer to find the best time to leave. Our 4D trajectory engine considers weather at each point along your route at the exact time you'll be there — not just at your destination. It also integrates live data from traffic cameras, DOT 511 feeds, and road weather sensors.
Frequently Asked Questions
How long is the drive from Greenville to Memphis?
The drive is approximately 493 miles and takes about 9h 51m under normal traffic and weather conditions. Severe weather can add significant time to your trip.
What's the best day to drive this route?
Based on current forecasts, Tomorrow (Nov 15) looks ideal. Clear conditions expected along the entire route
Is it safe to drive from Greenville to Memphis today?
Current conditions show high risk along this route. Conditions look favorable for travel. Always stay alert and adjust speed for changing conditions.
Are there rest areas on the Greenville to Memphis route?
Yes, there are 44 rest areas along this route. Facilities include restrooms, parking, and in some cases picnic areas and vending machines. Rest stops are spaced throughout the drive, so you'll never be too far from a break.
Can I see live traffic cameras on this route?
Yes, Route Outlook shows 12 live traffic cameras along this route, sourced from state DOT feeds. You can check road visibility, traffic flow, and pavement conditions in real time before and during your drive.
What highways does this route use?
This route primarily uses I-10 West. Conditions can vary between highway segments, so check live camera feeds and road condition reports for each stretch before departing.
Are there any road closures on this route right now?
No significant incidents or road closures are currently reported along this route. Conditions can change quickly — this page updates automatically with the latest data from state DOT 511 systems.
Related Driving Guides
Finding the Safest Time to Drive: A Data-Driven Approach
Learn how 4D trajectory analysis can help you find the optimal departure time to avoid dangerous weather and traffic.
🛣️How to Check Road Conditions Before a Trip: All Your Options
A practical guide to every method for checking driving conditions--weather apps, 511 sites, traffic cameras, radio, and more. Pros, cons, and when to use each.
🧠Route Intelligence: The Smarter Way to Plan Road Trips
Stop checking weather at your destination. Start knowing what you'll actually drive through--and when. Here's how Route Intelligence changes everything.
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