Winona, MN → Indianapolis, IN
408 mi · 8h 10m (driving)
Current Risk
Low Risk
Clear conditions along your route
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Winona
29°
Town of Linden
35°
DeKalb County
37°
Iroquois County
38°
Indianapolis
40°
Trip Briefing
4 segments · 408 mi · 8h 10m
Weather
⛅ Partly cloudy
35°F, wind 11 mph
Rest Stops
15
Restrooms, Truck svc
Cameras
3 live
Clear driving conditions expected
Rest stops in this segment:
- ● Nodine Truck Stop
- ● Dresbach Rest Area 🚻
- ● La Crosse Rest Area 31 🚻
Hazards Ahead
13 road closures may affect your route · 29 construction zones on route
29 Construction Zones on Route
WI-21 eastbound: Roadwork - Mainline Flagging Operation on WIS 21 EB from County B to N Rusk Ave. Daily from 11/09/2026 to 11/13/2026, 07:00 AM - 05:00 PM, M, T, W, Th, F
WI-16 eastbound: Roadwork - Mainline Flagging Operation on WIS 16 EB from Hollister Ave to US 12 WB (End Divided). Daily from 11/09/2026 to 11/13/2026, 07:00 AM - 05:00 PM, M, T, W, Th, F
WI-16 eastbound: Roadwork - Mainline Right Lane Closed on WIS 16 EB from US 12 EB (Begin CC) to Sime Ave. Daily from 11/09/2026 to 12/11/2026, 07:00 AM - 04:00 PM, M, T, W, Th, F (excluding Sun, Sat)
US-12 eastbound: Roadwork - Mainline Flagging Operation on US 12 EB from Grain Ave to Monroe - Juneau CO Line. Daily from 08/26/2026 to 11/30/2026, 06:30 AM - 06:30 PM, M, T, W, Th, F (excluding Sun, Sat)
WI-16 eastbound: Roadwork - Mainline Flagging Operation on WIS 16 EB from Monroe - Juneau CO Line to Leer St. Daily from 08/26/2026 to 11/30/2026, 06:30 AM - 06:30 PM, M, T, W, Th, F (excluding Sun, Sat)
US-12 eastbound: Long-term: Roadwork - Mainline Left Lane Closed on US 12 EB from US 12 WB (Begin Divided) to Munroe St. Detour: US 12 EB to WIS 13 SB to I-90/94 EB to WIS 23 NB to US 12 EB
+ 23 more zones along the route — see map for full list
Highway Message Signs
US 12/18 US 12/18 EB @ E of West Broadway (MM 264.2)
FLEX LANE | CLOSED TO TRAFFIC | SILVER ALERT | WHITE HONDA SUV | WI LIC: AZJ2933
US 12/18 US 12/18 WB @ W of Stoughton Rd (MM 265.6)
FLEX LANE | CLOSED TO TRAFFIC | SILVER ALERT | WHITE HONDA SUV | WI LIC: AZJ2933
US 12/18 US 12/18 WB @ Agriculture/Marsh Dr
FLEX LANE | CLOSED TO TRAFFIC | SILVER ALERT | WHITE HONDA SUV | WI LIC: AZJ2933
I-39/90 I-39/90 NB/WB @ S of Woodman Rd
LEFT SHOULDER | BLOCKED | 5 MILES AHEAD | SILVER ALERT | WHITE HONDA SUV | WI LIC: AZJ2933
Traffic Cameras
See recent road conditions along your route
Images are snapshots updated periodically by state DOTs. Timestamps shown in images indicate when each photo was captured.
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Via US-14 East → US-61 South → ... → I-294 South → I-65 South
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I-90 EB (La Crescent - MP 276.4) View 4
MN · EB
I-90 at WIS 131
Monroe, WI ·
I-90/94 at County C
Juneau, WI ·
I-90/94 at WIS 23
Sauk, WI ·
I-90 EB: Randall Rd at I-90EB
IL · EB
I-90 EB: Cumberland HD (view 1)
IL · EB
I-39/90/94 at WIS 19
Dane, WI ·
I-39/90 at Milwaukee St
Rock, WI ·
I-294 SB: IL394 s/o I-80
IL · SB
I-65 MP 242.2 163RD AVE (view 2)
IN ·
US 231 S JCT
IN ·
I-65/149.6 SB LEBANON REST AREA (view 5)
IN · SB
Live traffic on this route
Cameras, crashes and closures right now on the highways this drive uses.
Rest Stops Along Your Route
93 stops available
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⚡ Recent Weather Events on This Route
Premium users received alerts for these conditions:
- 🌧️Nov 11: Heavy rain expected near DeKalb County - consider afternoon departure
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Driving from Winona, MN to Indianapolis, IN covers 408 miles in roughly 8h 10m of drive time, crossing state lines. We track 12 live traffic cameras, 93 rest areas and 13 reported incidents along this corridor so you can plan around them. Most drivers do this trip in one day; weather along the route matters more than the forecast at either endpoint, since you'll cross several climate zones.
7-Day Driving Outlook
Today
Nov 13
38° / 29°
No precip
Tomorrow
Nov 14
42° / 27°
No precip
Sun
Nov 15
47° / 28°
No precip
Mon
Nov 16
48° / 31°
No precip
Tue
Nov 17
51° / 36°
No precip
Wed
Nov 18
53° / 40°
No precip
Thu
Nov 19
53° / 51°
No precip
🗓️ Weekend Outlook
Saturday
Good to Go🌤️ Mainly clear at origin, ☁️ Overcast at destination
Sunday
Good to Go🌫️ Fog at origin, ☁️ Overcast at destination
Plan This Route
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Current Conditions
Winona, MN
29°F
Wind: 7 mph
Indianapolis, IN
40°F
Wind: 9 mph
Weather data updated in real-time
Driving from Winona, MN to Indianapolis, IN
The 408-mile drive from Winona, Minnesota to Indianapolis, Indiana takes approximately 8h 10m under normal conditions. Weather along this route can vary significantly, especially across open plains where severe weather and high winds can develop quickly. Route Outlook helps you find the safest time to travel by showing you weather conditions at every point along your route, timed to when you'll actually be there.
This long-distance route crosses state lines from Minnesota into Indiana, connecting Winona and Indianapolis. Covering 408 miles, this is a substantial drive that will take you through diverse terrain and weather patterns. Planning ahead with real-time conditions along the entire route — not just at your destination — is essential for a safe trip.
Common Weather Hazards on This Route
- Winter storms and heavy snowfall (November through April)
- Black ice on mountain passes and bridges
- Dense fog, especially during early morning hours
Seasonal Driving Considerations
The Midwest corridor of this route is susceptible to rapid weather changes. Severe thunderstorms and tornadoes are a real threat from April through June, while winter brings heavy lake-effect snow, ice storms, and dangerously low wind chill. Flat terrain means high crosswinds can affect vehicle stability year-round, especially for taller vehicles. Spring flooding can also close highway underpasses and low-lying road segments.
Best Time to Drive Winona to Indianapolis
For medium-distance drives like this 408-mile route, consider starting in the early morning to arrive before afternoon storms develop. Check the 7-day forecast above to find a day with favorable conditions along the entire route.
Driving Strategy
A 408-mile drive from Winona to Indianapolis takes a significant part of the day. Plan at least one fuel and rest stop along the way. If your route crosses elevation changes or state lines, expect weather conditions to shift mid-trip. Monitor the segment-by-segment forecast rather than just checking destination weather. Starting early in the morning typically avoids afternoon storm development and rush-hour congestion near urban areas.
Pro Tip
Use Route Outlook's departure optimizer to find the best time to leave. Our 4D trajectory engine considers weather at each point along your route at the exact time you'll be there — not just at your destination. It also integrates live data from traffic cameras, DOT 511 feeds, and road weather sensors.
Frequently Asked Questions
How long is the drive from Winona to Indianapolis?
The drive is approximately 408 miles and takes about 8h 10m under normal traffic and weather conditions. Severe weather can add significant time to your trip.
What's the best day to drive this route?
Based on current forecasts, Monday, Nov 16 looks ideal. Clear conditions expected along the entire route
Is it safe to drive from Winona to Indianapolis today?
Current conditions show low risk along this route. Conditions look favorable for travel. Always stay alert and adjust speed for changing conditions.
Are there rest areas on the Winona to Indianapolis route?
Yes, there are 93 rest areas along this route. Facilities include restrooms, parking, and in some cases picnic areas and vending machines. Rest stops are spaced throughout the drive, so you'll never be too far from a break.
Can I see live traffic cameras on this route?
Yes, Route Outlook shows 12 live traffic cameras along this route, sourced from state DOT feeds. You can check road visibility, traffic flow, and pavement conditions in real time before and during your drive.
What highways does this route use?
This route primarily uses I-90 East, I-39 South, I-294 South, I-65 South. Conditions can vary between highway segments, so check live camera feeds and road condition reports for each stretch before departing.
Are there any road closures on this route right now?
There are currently 13 active incidents along this route that may affect your drive. Check the incident details above for specific locations and expected durations.
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🛡️Road Safety Features: Real-Time Conditions for Your Route
Real-time traffic incidents from 12 states, highway message signs, road conditions, and 25,000+ traffic cameras--integrated into your route planning.
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